Tétrazépam RPG

Tétrazépam RPG may be available in the countries listed below.

Ingredient matches for Tétrazépam RPG

Tetrazepam

Tetrazepam is reported as an ingredient of Tétrazépam RPG in the following countries:

• France

International Drug Name Search

Abacavir

Pronunciation: a-BAK-a-vir
Generic Name: Abacavir
Brand Name: Ziagen

Abacavir has caused severe and sometimes fatal allergic reactions. Contact your doctor right away if you develop fever; rash; nausea, vomiting, diarrhea, or stomach pain; cough; sore throat, or trouble breathing; unusual tiredness or achiness; or general feeling of being unwell. Do NOT take Abacavir again or take any other medicine that contains abacavir if you have had an allergic reaction to Abacavir. You may be at risk for an even more severe allergic reaction.

Patients who have a certain gene type called HLA-B^*5701 have an increased risk of allergic reaction. A lab test may be performed before you start Abacavir to see if you have this gene type. Discuss any questions or concerns with your doctor.

Abacavir may cause severe and sometimes fatal liver problems or high blood acid levels (lactic acidosis). Contact your doctor right away if you develop yellowing of the skin or eyes; dark urine; pale stools; stomach pain; nausea; vomiting; diarrhea; persistent loss of appetite; fast or difficult breathing; slow or irregular heartbeat; unusual weakness or tiredness; muscle pain or tenderness; unusual feeling of cold (eg, in arms or legs); or unusual drowsiness, dizziness, or lightheadedness.

Abacavir is used for:

Treating HIV infection with other medications.

Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI). It works by slowing down the growth of HIV, the virus that causes AIDS.

Do NOT use Abacavir if:

• you are allergic to any ingredient in Abacavir


• you have had a recent abnormal liver function test or have moderate to severe liver problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Abacavir:

Some medical conditions may interact with Abacavir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding or thinking about breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of heart problems (eg, heart attack), high blood pressure, high cholesterol, diabetes, or smoking


• if you have been tested and know whether or not you have a gene type called HLA-B^*5701

Some MEDICINES MAY INTERACT with Abacavir. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alcohol because it may increase the risk of Abacavir's side effects and toxic effects


• Methadone because its effectiveness may be decreased by Abacavir

This may not be a complete list of all interactions that may occur. Ask your health care provider if Abacavir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Abacavir:

Use Abacavir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Abacavir comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Abacavir refilled.


• Abacavir comes with a warning card that provides information about recognition of allergic reactions. Carry the warning card of allergy symptoms with you. Tell your health care provider immediately about any side effects you experience while taking Abacavir.


• Take Abacavir by mouth with or without food.


• Using Abacavir at the same times each day will help you remember to take it.


• Continue to take Abacavir even if you feel well. Do not miss any doses.


• If you miss a dose of Abacavir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Abacavir.

Important safety information:

• Talk to your doctor before you take Abacavir if you drink more than 3 drinks with alcohol per day.


• Tell your doctor or dentist that you take Abacavir before you receive any medical or dental care, emergency care, or surgery.


• If you must stop taking Abacavir for any reason other than a serious allergic reaction, do not start taking Abacavir again without talking with your health care provider. If your health care provider decides that you may take Abacavir again, you should do so only in a setting with other people in case you need immediate access to a doctor.


• When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Abacavir, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.


• Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Abacavir. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.


• Abacavir does not stop the spread of HIV to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.


• Abacavir is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.


• Lab tests, including liver function and monitoring for hypersensitivity reactions, may be performed while you use Abacavir. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Abacavir with caution in the ELDERLY; they may be more sensitive to its effects, especially liver, kidney, or heart problems.


• Caution is advised when using Abacavir in CHILDREN; they may be more sensitive to its effects, especially fever; chills; rash; or ear, nose, or throat infection.


• Abacavir should not be used in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Abacavir while you are pregnant. It is not known if Abacavir is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Abacavir to the baby.

Possible side effects of Abacavir:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; lack of energy; mild nausea; tiredness; trouble sleeping; unusual dreams; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, numbness, or tingling of the skin; change in the amount of urine produced; chest pain or discomfort, numbness of an arm or leg, or sudden vision changes; ear pain; eye pain, redness, or swelling; fainting; fever or chills; general feeling of being unwell; mental or mood changes (eg, depression); mouth sores; red, swollen, blistered, or peeling skin; severe or persistent dizziness; severe or persistent nausea, vomiting, or diarrhea; shortness of breath, cough, or sore throat; stomach pain; swollen lymph nodes; symptoms of lactic acidosis (eg, fast breathing; muscle pain; unusual cold feeling in the arms or legs; sluggishness; unusual drowsiness, dizziness, or lightheadedness); symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, loss of appetite, severe or persistent tiredness); unusual achiness or swelling.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Abacavir side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Abacavir:

Store Abacavir at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Abacavir out of the reach of children and away from pets.

General information:

• If you have any questions about Abacavir, please talk with your doctor, pharmacist, or other health care provider.


• Abacavir is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Abacavir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Abacavir resources

• Abacavir Side Effects (in more detail)
• Abacavir Dosage
• Abacavir Use in Pregnancy & Breastfeeding
• Abacavir Drug Interactions
• Abacavir Support Group
• 0 Reviews for Abacavir - Add your own review/rating

• abacavir Advanced Consumer (Micromedex) - Includes Dosage Information


• abacavir Concise Consumer Information (Cerner Multum)


• Abacavir Sulfate Monograph (AHFS DI)


• Ziagen Prescribing Information (FDA)

Compare Abacavir with other medications

• HIV Infection
• Nonoccupational Exposure

rifapentine

rif-a-PEN-teen

Commonly used brand name(s)

In the U.S.

• Priftin

Available Dosage Forms:

• Tablet

Therapeutic Class: Antitubercular

Chemical Class: Rifamycin

Uses For rifapentine

Rifapentine is used with other medicines to treat tuberculosis.

To help clear up your tuberculosis completely, you must keep taking rifapentine for the full time of treatment, even if you begin to feel better. This is very important. It is also important that you do not miss any doses.

Rifapentine is available only with your doctor's prescription.

Before Using rifapentine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rifapentine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to rifapentine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Safety and efficacy have not been established in infants and children younger than 12 years of age. For children 12 years of age and older, rifapentine is not expected to cause different side effects or problems than it does in adults.

Geriatric

Rifapentine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking rifapentine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using rifapentine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Ranolazine


• Rilpivirine

Using rifapentine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abiraterone


• Amprenavir


• Bortezomib


• Cabazitaxel


• Efavirenz


• Erlotinib


• Etravirine


• Everolimus


• Fosamprenavir


• Indinavir


• Lapatinib


• Nevirapine


• Nilotinib


• Rivaroxaban


• Romidepsin


• Sunitinib


• Ticagrelor


• Tolvaptan


• Vandetanib


• Vemurafenib

Using rifapentine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol


• Acetyldigoxin


• Alprazolam


• Amiodarone


• Amitriptyline


• Amlodipine


• Betamethasone


• Bisoprolol


• Carbamazepine


• Carteolol


• Carvedilol


• Chloramphenicol


• Chlorpropamide


• Ciprofloxacin


• Clarithromycin


• Clofibrate


• Cyclosporine


• Dapsone


• Delavirdine


• Deslanoside


• Desogestrel


• Dexamethasone


• Diazepam


• Dicumarol


• Dienogest


• Digitoxin


• Digoxin


• Diltiazem


• Disopyramide


• Doxycycline


• Drospirenone


• Estradiol Cypionate


• Estradiol Valerate


• Ethinyl Estradiol


• Ethynodiol Diacetate


• Etonogestrel


• Felodipine


• Fluconazole


• Fludrocortisone


• Fosphenytoin


• Gallopamil


• Glyburide


• Haloperidol


• Hydrocortisone


• Isradipine


• Itraconazole


• Ketoconazole


• Lacidipine


• Lercanidipine


• Levonorgestrel


• Levothyroxine


• Lorcainide


• Medroxyprogesterone Acetate


• Mestranol


• Metildigoxin


• Metoprolol


• Mexiletine


• Nelfinavir


• Nicardipine


• Nifedipine


• Nimodipine


• Nisoldipine


• Nitrazepam


• Nitrendipine


• Norelgestromin


• Norethindrone


• Norgestimate


• Norgestrel


• Nortriptyline


• Phenprocoumon


• Phenytoin


• Prednisone


• Propafenone


• Propranolol


• Quinidine


• Quinine


• Repaglinide


• Ritonavir


• Saquinavir


• Sildenafil


• Tacrolimus


• Talinolol


• Temazepam


• Tertatolol


• Theophylline


• Tocainide


• Tolbutamide


• Triazolam


• Valproic Acid


• Verapamil


• Warfarin


• Zidovudine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of rifapentine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse (or history of) or


• Liver disease—There may be an increased chance of side effects affecting the liver in patients with a history of alcohol abuse or liver disease

Proper Use of rifapentine

The treatment of tuberculosis may take months or years to complete. It is very important that you comply with the full course of therapy.

Dosing

The dose of rifapentine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of rifapentine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For the treatment of tuberculosis (TB):
    
    • Adults and children 12 years of age and older—600 milligrams (mg) twice a week with an interval of not less than three days (seventy-two hours) between doses. Rifapentine must be taken with other medicines to treat tuberculosis.
    
    
    • Infants and children up to 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of rifapentine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using rifapentine

It is very important that your doctor check your progress at regular visits.

If your symptoms do not improve within 2 to 3 weeks, or if they become worse, check with your doctor.

If rifapentine causes you to feel very tired or very weak or causes a loss of appetite, nausea, or vomiting, stop taking it and check with your doctor immediately. These may be early warning signs of more serious problems that could develop later.

Oral contraceptives (birth control pills) may not work properly if you take them while you are taking rifapentine. Unplanned pregnancies may occur. You should use a different means of birth control while you are taking rifapentine. If you have any questions about this, check with your health care professional.

Liver problems may be more likely to occur if you drink alcoholic beverages regularly while you are taking rifapentine. Also, the regular use of alcohol may keep rifapentine from working properly. Therefore, you should not drink alcoholic beverages while you are taking rifapentine .

Rifapentine will cause the urine, stools, saliva, sputum, sweat, and tears to turn reddish-orange to reddish-brown. This is to be expected while you are taking rifapentine. This effect may cause soft contact lenses to become permanently discolored. Standard cleaning solutions may not take out all the discoloration. Therefore, it is best not to wear soft contact lenses while taking rifapentine. Hard contact lenses are not discolored by rifapentine. If you have any question about this, check with your doctor.

Rifapentine can lower the number of white blood cells in your blood temporarily, increasing the chance of getting infection. It can also lower the number of platelets, which are necessary for proper blood clotting. These problems may result in a greater chance of getting certain infections, slow healing, and bleeding of the gums. Be careful when using a regular toothbrush, dental floss, or a toothpick. Dental work should be delayed until your blood counts have returned to normal. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.

Before you have any medical tests, tell the doctor in charge that you are taking rifapentine.

rifapentine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Blood in urine


• joint pain


• lower back or side pain


• swelling of feet or lower legs

Less common

• Aggressive reaction


• black, tarry stools


• blood in stools


• nausea


• pinpoint red spots on skin


• severe abdominal or stomach pain


• sore throat and fever


• unusual bleeding or bruising


• unusual tiredness or weakness


• yellow eyes or skin


• vomiting

Rare

• Diarrhea


• dizziness


• severe or continuing headaches


• increase in blood pressure

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Acne


• constipation


• loss of appetite

rifapentine commonly causes reddish-orange to reddish-brown discoloration of urine, stools, saliva, sputum, sweat, and tears. This side effect does not usually need medical attention.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: rifapentine side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More rifapentine resources

• Rifapentine Side Effects (in more detail)
• Rifapentine Dosage
• Rifapentine Use in Pregnancy & Breastfeeding
• Rifapentine Drug Interactions
• Rifapentine Support Group
• 0 Reviews for Rifapentine - Add your own review/rating

• rifapentine Concise Consumer Information (Cerner Multum)


• Rifapentine Professional Patient Advice (Wolters Kluwer)


• Rifapentine MedFacts Consumer Leaflet (Wolters Kluwer)


• Rifapentine Monograph (AHFS DI)


• Priftin Prescribing Information (FDA)

Compare rifapentine with other medications

• Tuberculosis, Active

Subutex

In the US, Subutex (buprenorphine systemic) is a member of the drug class narcotic analgesics and is used to treat Opiate Dependence.

US matches:

• Subutex

Ingredient matches for Subutex

Buprenorphine

Buprenorphine is reported as an ingredient of Subutex in the following countries:

• Poland

Buprenorphine hydrochloride (a derivative of Buprenorphine) is reported as an ingredient of Subutex in the following countries:

• Australia


• Austria


• Belgium


• Bulgaria


• Croatia (Hrvatska)


• Czech Republic


• Denmark


• Estonia


• Finland


• France


• Germany


• Greece


• Hong Kong


• Iceland


• Indonesia


• Ireland


• Israel


• Italy


• Latvia


• Lithuania


• Luxembourg


• Malaysia


• Malta


• Norway


• Portugal


• Singapore


• Slovakia


• Slovenia


• South Africa


• Sweden


• Switzerland


• United Kingdom


• United States

International Drug Name Search

Seloken L

Seloken L may be available in the countries listed below.

Ingredient matches for Seloken L

Metoprolol

Metoprolol tartrate (a derivative of Metoprolol) is reported as an ingredient of Seloken L in the following countries:

• Japan

International Drug Name Search

Risperidone-GA

Risperidone-GA may be available in the countries listed below.

Ingredient matches for Risperidone-GA

Risperidone

Risperidone is reported as an ingredient of Risperidone-GA in the following countries:

• Australia

International Drug Name Search

Sixdin

Sixdin may be available in the countries listed below.

Ingredient matches for Sixdin

Conjugated Estrogens

Estrogens, conjugated is reported as an ingredient of Sixdin in the following countries:

• Mexico

International Drug Name Search

Sulfachinossalina

Sulfachinossalina may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Sulfachinossalina

Sulfaquinoxaline

Sulfaquinoxaline is reported as an ingredient of Sulfachinossalina in the following countries:

• Italy

Sulfaquinoxaline sodium salt (a derivative of Sulfaquinoxaline) is reported as an ingredient of Sulfachinossalina in the following countries:

• Italy

International Drug Name Search

Sulfasol

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Sulfasol

Sulfadimethoxine

Sulfadimethoxine is reported as an ingredient of Sulfasol in the following countries:

• United States

Sulfafurazole

Sulfafurazole is reported as an ingredient of Sulfasol in the following countries:

• Bosnia & Herzegowina


• Croatia (Hrvatska)


• Slovenia

International Drug Name Search

Propanidid

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

N01AX04

CAS registry number (Chemical Abstracts Service)

0001421-14-3

Chemical Formula

C18-H27-N-O5

Molecular Weight

337

Therapeutic Category

Anesthetic, injectable

Chemical Name

Benzeneacetic acid, 4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester

Foreign Names

• Propanididum (Latin)
• Propanidid (German)
• Propanidide (French)
• Propanidida (Spanish)

Generic Names

• Propanidid (OS: BAN, USAN)
• Propanidide (OS: DCF)
• Bayer 1420 (IS)
• FBA 1420 (IS)
• Propanidid (PH: BP 1988)

Brand Names

• Panitol
  Cryopharma, Mexico



• Progray
  Gray, Argentina

International Drug Name Search

Glossary

BAN	British Approved Name
DCF	Dénomination Commune Française
IS	Inofficial Synonym
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Cacit Vitamina D3

Cacit Vitamina D3 may be available in the countries listed below.

Ingredient matches for Cacit Vitamina D3

Calcium Carbonate

Calcium Carbonate is reported as an ingredient of Cacit Vitamina D3 in the following countries:

• Belgium


• Italy


• United Kingdom

Colecalciferol

Colecalciferol is reported as an ingredient of Cacit Vitamina D3 in the following countries:

• Belgium


• Italy


• United Kingdom

International Drug Name Search

Nagifen

Nagifen may be available in the countries listed below.

Ingredient matches for Nagifen

Ibuprofen

Ibuprofen is reported as an ingredient of Nagifen in the following countries:

• Japan

International Drug Name Search

Stibatin

Stibatin may be available in the countries listed below.

Ingredient matches for Stibatin

Sodium Stibogluconate

Sodium Stibogluconate is reported as an ingredient of Stibatin in the following countries:

• Bangladesh

International Drug Name Search

Avlocillin

Avlocillin may be available in the countries listed below.

Ingredient matches for Avlocillin

Ampicillin

Ampicillin trihydrate (a derivative of Ampicillin) is reported as an ingredient of Avlocillin in the following countries:

• Bangladesh

International Drug Name Search

Selsun Blue Moisturizing Treatment

Generic Name: selenium sulfide topical (se LEE nee um SUL fide TOP ik al)

Brand Names: Dandrex, Head & Shoulders Intensive Treatment, Selenos, Selseb, Selsun Blue, Selsun Blue 2 in 1, Selsun Blue Balanced Treatment, Selsun Blue Moisturizing Treatment, Tersi Foam

What is Selsun Blue Moisturizing Treatment (selenium sulfide topical)?

Selenium sulfide is an antifungal medication. It prevents fungus from growing on your skin.

Selenium sulfide topical (for the skin) is used to treat dandruff, seborrhea, and tinea versicolor (a fungus that discolors the skin).

Selenium sulfide topical may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Selsun Blue Moisturizing Treatment (selenium sulfide topical)?

Avoid getting this medication in your eyes, nose, or mouth. If it does get into any of these areas, rinse with water. Do not use selenium sulfide topical on sunburned, windburned, dry, chapped, or broken skin.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Do not cover treated skin with a bandage or other dressing unless your doctor has told you to. A light cotton-gauze bandage may be used to protect clothing. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.

Stop using selenium sulfide and call your doctor if you have unusual or severe blistering, itching, redness, peeling, dryness, or irritation of the skin.

What should I discuss with my healthcare provider before using Selsun Blue Moisturizing Treatment (selenium sulfide topical)?

You should not use this medication if you are allergic to selenium sulfide. FDA pregnancy category C. It is not known whether selenium sulfide is harmful to an unborn baby. Before using selenium sulfide topical, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether selenium sulfide passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Selsun Blue Moisturizing Treatment (selenium sulfide topical)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Shake the selenium sulfide foam well just before each use. Wash your hands after applying this medication.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Do not cover treated skin with a bandage or other dressing unless your doctor has told you to. A light cotton-gauze bandage may be used to protect clothing.

Store this medication at room temperature away from moisture and heat. Keep the medicine canister away from open flame, and do not puncture the can.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not apply extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of selenium sulfide topical is not likely to produce life-threatening side effects.

What should I avoid while using Selsun Blue Moisturizing Treatment (selenium sulfide topical)?

Avoid getting this medication in your eyes, nose, mouth, rectum, or vagina. If it does get into any of these areas, rinse with water. Do not use selenium sulfide topical on sunburned, windburned, dry, chapped, or broken skin.

Avoid covering treated skin areas with tight-fitting, synthetic clothing that doesn't allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.

Selsun Blue Moisturizing Treatment (selenium sulfide topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using selenium sulfide and call your doctor if you have unusual or severe blistering, itching, redness, peeling, dryness, or irritation of the skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Selsun Blue Moisturizing Treatment (selenium sulfide topical)?

Avoid using other topical medications at the same time you apply selenium sulfide topical, unless your doctor approves. Other skin medications may affect the absorption or effectiveness of selenium sulfide topical.

More Selsun Blue Moisturizing Treatment resources

• Selsun Blue Moisturizing Treatment Side Effects (in more detail)
• Selsun Blue Moisturizing Treatment Use in Pregnancy & Breastfeeding
• Selsun Blue Moisturizing Treatment Support Group
• 0 Reviews for Selsun Blue Moisturizing Treatment - Add your own review/rating

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Compare Selsun Blue Moisturizing Treatment with other medications

• Seborrheic Dermatitis
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Where can I get more information?

• Your pharmacist can provide more information about selenium sulfide topical.

See also: Selsun Blue Moisturizing Treatment side effects (in more detail)

Xyzal

Generic Name: Levocetirizine Dihydrochloride
Class: Second Generation Antihistamines
Chemical Name: [2-[4-[(R)-p-Chloro-α-phenylbenzyl]-1-piperazinyl]ethoxy]acetic acid
Molecular Formula: C₂₁H₂₅ClN₂O₃
CAS Number: 130018-77-8

Special Alerts:

[Posted 10/09/2008] FDA notified healthcare professionals and consumers that the Consumer Healthcare Products Association (CHPA) is voluntarily modifying the product labels for consumers of over the counter (OTC) cough and cold medicines to state “do not use” in children under 4 years of age. FDA supports CHPA members to help prevent and reduce misuse and to better inform consumers about the safe and effective use of these products for children. FDA continues to assess the safety and efficacy of these products and to revise its OTC list of approved ingredients and amounts for these medicines. Parents and care givers should adhere to the dosage instructions and warnings on the label that accompanies OTC cough and cold medications before giving the product to children, and should consult their healthcare professionals if they have any questions or concerns. For more information visit the FDA website at: and .

Introduction

Second generation antihistamine;³⁴ R-enantiomer of cetirizine.^{1 2 3 4 5 7 14 15}

Uses for Xyzal

Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

Allergic Rhinitis

Symptomatic relief of seasonal (e.g., hay fever) and perennial (nonseasonal) allergic rhinitis.^{1 5 12 15 32}

Chronic Idiopathic Urticaria

Symptomatic treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.^{1 5 13 14}

Xyzal Dosage and Administration

Administration

Oral Administration

Administer orally once daily in the evening without regard to meals.¹

Tablets are scored and can be broken in 2 halves (each providing a dose of 2.5 mg).¹

Dosage

Available as levocetirizine dihydrochloride; dosage expressed in terms of the salt.¹

Pediatric Patients

Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

Allergic Rhinitis

Oral

Children 6–11 years of age: 2.5 mg once daily.¹ (See Pediatric Use under Cautions.)

Children ≥12 years of age: 5 mg once daily; alternatively, 2.5 mg once daily may be adequate for some patients.¹

Chronic Idiopathic Urticaria

Oral

Children 6–11 years of age: 2.5 mg once daily.¹ (See Pediatric Use under Cautions.)

Children ≥12 years of age: 5 mg once daily; alternatively, 2.5 mg once daily may be adequate for some patients.¹

Adults

Allergic Rhinitis

Oral

5 mg once daily; alternatively, 2.5 mg once daily may be adequate for some patients.¹

Chronic Idiopathic Urticaria

Oral

5 mg once daily; alternatively, 2.5 mg once daily may be adequate for some patients.¹

Prescribing Limits

Pediatric Patients

Allergic Rhinitis

Oral

Children 6–11 years of age: Maximum 2.5 mg daily.¹ (See Absorption: Special Populations, under Pharmacokinetics.)

Children ≥12 years of age: Maximum 5 mg daily.¹

Chronic Idiopathic Urticaria

Oral

Children 6–11 years of age: Maximum 2.5 mg daily.¹ (See Absorption: Special Populations, under Pharmacokinetics.)

Children ≥12 years of age: Maximum 5 mg daily.¹

Adults

Allergic Rhinitis

Oral

Maximum 5 mg daily;¹ higher dosages (e.g., 10 mg daily) associated with increased risk of somnolence.^{1 15}

Chronic Idiopathic Urticaria

Oral

Maximum 5 mg daily;¹ higher dosages (e.g., 10 mg daily) associated with increased risk of somnolence.^{1 15}

Special Populations

Hepatic Impairment

No dosage adjustment required.¹

Renal Impairment

Children 6–11 years of age: Use contraindicated.¹ (See Contraindications under Cautions.)

Adults and children ≥12 years of age: Adjust dosage based on degree of renal impairment. (See Table.)

Table 1. Dosage for Symptomatic Treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria in Adults and Children ≥12 Years of Age with Renal Impairment133

Clcr (mL/minute)	Dosage
50–80	2.5 mg once daily
30–50	2.5 mg every other day
10–30	2.5 mg twice weekly (administered every 3–4 days)
<10 (or undergoing hemodialysis)	Use contraindicated

Geriatric Patients

Select dosage with caution (usually starting at low end of dosage range) because of age-related decreases in hepatic, renal, and/or cardiac function and concomitant disease and drug therapy.¹ (See Geriatric Use under Cautions.)

Cautions for Xyzal

Contraindications

• 
  

  Known hypersensitivity to levocetirizine or any ingredient in the formulation, or to cetirizine.¹

  
  


• 
  

  Adults and children ≥12 years of age with end-stage renal disease (Cl_cr <10 mL/minute) or undergoing hemodialysis.¹

  
  


• 
  

  Pediatric patients 6–11 years of age with renal impairment.¹

  
  

Warnings/Precautions

General Precautions

CNS Effects

Somnolence, fatigue, and asthenia reported.^{1 7 12 13 15} Caution required when performing hazardous activities requiring mental alertness or physical coordination (e.g., operating machinery, driving a motor vehicle).¹ (See Advice to Patients.)

Specific Populations

Pregnancy

Category B.¹

Lactation

Expected to distribute into milk (as cetirizine is distributed into milk).¹ Use not recommended.¹

Pediatric Use

Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

Safety and efficacy not established in children <6 years of age.¹

Efficacy of 2.5-mg daily dosage for management of allergic rhinitis or chronic idiopathic urticaria in children 6–11 years of age is based on extrapolation of demonstrated efficacy of 5-mg daily dosage in children ≥12 years of age and on pharmacokinetic comparisons in adults and children.¹

Efficacy of 5-mg daily dosage for management of chronic idiopathic urticaria in children ≥12 years of age is based on extrapolation of demonstrated efficacy in adults.¹

Risk of overdosage and toxicity (including death) in children <2 years of age receiving OTC preparations containing antihistamines, cough suppressants, expectorants, and nasal decongestants alone or in combination for relief of symptoms of upper respiratory tract infection. Limited evidence of efficacy for these preparations in this age group; appropriate dosages not established. Therefore, FDA recommended not to use such preparations in children <2 years of age; safety and efficacy in older children currently under evaluation. Because children 2–3 years of age also are at increased risk of overdosage and toxicity, some manufacturers of oral nonprescription cough and cold preparations recently agreed to voluntarily revise the product labeling to state that such preparations should not be used in children <4 years of age. During the transition period, some preparations on pharmacy shelves will have the new recommendation (“do not use in children <4 years of age”), while others will have the previous recommendation (“do not use in children <2 years of age”). FDA recommends that parents and caregivers adhere to dosage instructions and warnings on the product labeling that accompanies the preparation and consult a clinician about any concerns. Clinicians should ask caregivers about use of nonprescription cough and cold preparations to avoid overdosage.

Geriatric Use

Insufficient experience in patients ≥65 years of age to determine whether geriatric patients respond differently than younger adults.¹ Select dosage with caution because of age-related decreases in hepatic, renal, and/or cardiac function and concomitant disease and drug therapy.¹ (See Geriatric Patients under Dosage and Administration.) Periodic monitoring of renal function may be useful.¹

Hepatic Impairment

Pharmacokinetics not evaluated, but clearance unlikely to be decreased.¹ (See Elimination under Pharmacokinetics.) Dosage adjustment not necessary.¹

Renal Impairment

Decreased clearance, resulting in increased risk of adverse effects.¹ Dosage adjustment necessary based on degree of renal impairment.¹ (See Renal Impairment under Dosage and Administration.)

Common Adverse Effects

Children 6–12 years of age (with 5-mg daily dosage): Pyrexia,¹ cough,¹ somnolence,¹ epistaxis.^{1 6}

Adults and children ≥12 years of age: Somnolence,^{1 5 15 32} nasopharyngitis,¹ fatigue,^{1 5 15 32} dry mouth,^{1 5 15} pharyngitis.^{1 32}

Interactions for Xyzal

No formal drug interaction studies with levocetirizine to date; studies have been performed with racemic cetirizine.¹ (See Specific Drugs under Interactions.)

Does not inhibit CYP isoenzymes 1A2, 2C9, 2C19, 2A1, 2D6, 2E1, or 3A4.^{1 5} Does not induce UGT1A or CYP isoenzymes 1A2, 2C9, or 3A4.¹ Unlikely to produce or be subject to pharmacokinetic interactions associated with metabolic enzyme systems.¹

Specific Drugs

Drug	Interaction	Comments
Azithromycin	No clinically important changes in ECG parameters observed following concomitant use with cetirizine, and no clinically important interactions reported following such concomitant use1 16 17 20 21
Cimetidine	No pharmacokinetic interactions observed with cetirizine1
CNS depressants (e.g., alcohol)	Possible additive CNS effects1	Avoid concomitant use1
Erythromycin	No clinically important changes in ECG parameters observed following concomitant use with cetirizine, and no clinically important interactions reported following such concomitant use1 16 17 20 21
Ketoconazole	Prolongation of QTc interval (with an increase of 17.4 msec) observed following concomitant administration with cetirizine; no other clinically important interactions reported following such concomitant use1 16 21 22	Not considered clinically important16 21 22
Pseudoephedrine	No pharmacokinetic interactions observed with cetirizine1 16 17
Ritonavir	Increased plasma AUC (42%), increased half-life (53%), and decreased clearance (29%) of cetirizine; disposition of ritonavir not altered following concomitant administration with cetirizine1
Theophylline	Decreased clearance (16%) of cetirizine; disposition of theophylline not altered following concomitant administration with cetirizine1 16 17

Xyzal Pharmacokinetics

Absorption

Bioavailability

Rapidly and extensively absorbed following oral administration, with peak plasma concentration usually attained in 0.9 hour.^{1 5 18}

Onset

Antihistaminic effects occur within 1 hour.^{1 2 7 19} Symptomatic improvement observed as early as 1 day after initiation of therapy for allergic rhinitis^{1 7 8 15} or chronic idiopathic urticaria.^{13 14 33}

Duration

Antihistaminic effects persist for at least 24 hours.^{1 2 6 7 8 15 19}

Food

A high-fat meal reduces peak plasma concentration by about 36% and delays time to peak plasma concentration by about 1.25 hours, but does not affect AUC.¹

Special Populations

In patients with renal impairment, AUC is increased by 1.8-, 3.2-, or 4.3-fold in those with mild, moderate, or severe impairment, respectively; AUC is increased by 5.7-fold in those with end-stage renal disease.¹

In pediatric patients, peak plasma concentration and AUC following administration of 5-mg dose is approximately twice that in adults.¹

Distribution

Extent

Average apparent volume of distribution is 0.4 L/kg, which represents distribution in total body water.¹

Expected to distribute into milk.¹

Plasma Protein Binding

Approximately 91–92%¹ (mainly albumin).^{5 33}

Elimination

Metabolism

Metabolized to a limited extent (<14% of dose) by aromatic oxidation, N-dealkylation, O-dealkylation, and taurine conjugation.¹

Elimination Route

Excreted in urine (85.4%) (via glomerular filtration and active tubular secretion) and in feces (12.9%).^{1 18}

<10% of dose removed by standard 4-hour hemodialysis procedure.¹

Half-life

Approximately 8 hours.¹

Special Populations

In patients with renal impairment, half-life is increased by 1.4-, 2-, or 2.9-fold in those with mild, moderate, or severe impairment, respectively; half-life is increased by fourfold in those with end-stage renal disease.¹ Total body clearance also progressively decreases based on severity of renal impairment.¹ (See Renal Impairment under Dosage and Administration.)

In pediatric patients receiving a single 5-mg dose, total body clearance was 30% greater and elimination half-life 24% shorter than those observed in adults.¹

In geriatric patients receiving 30 mg once daily for 6 days, total body clearance was 30% lower than that observed in younger adults; however, levocetirizine disposition appears to be dependent on renal function rather than on age.¹

Stability

Storage

Oral

Tablets

20–25ºC (may be exposed to 15–30ºC).^{1 33}

ActionsActions

• 
  

  Exhibits selective antagonism of peripheral histamine H₁-receptors.¹

  
  


• 
  

  At half the dosage of cetirizine, appears to be as potent as cetirizine in inhibiting histamine-induced sneezing,⁴ increased nasal airway resistance,^{3 4 5} and skin wheal and flare.^{2 3 5}

  
  


• 
  

  Has been shown to exhibit greater and more consistent inhibition of histamine-induced wheal and flare compared with other antihistamines (e.g., desloratadine, fexofenadine, loratadine).^{5 7 19} Clinical relevance of histamine wheal skin testing is unknown.¹

  
  

Advice to Patients

Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.

• 
  

  Importance of taking only as prescribed; do not exceed prescribed dosage.¹

  
  


• 
  

  Risk of somnolence;^{1 7 12 15} exercise caution when performing activities requiring mental alertness or physical coordination (e.g., operating machinery, driving a motor vehicle).¹

  
  


• 
  

  Avoid concomitant use with alcohol or other CNS depressants.¹

  
  


• 
  

  Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs and dietary or herbal supplements, as well as any concomitant illnesses.¹

  
  


• 
  

  Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed.¹

  
  


• 
  

  Importance of informing patients of other important precautionary information.¹ (See Cautions.)

  
  

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Levocetirizine Dihydrochloride

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Oral	Tablets, film-coated	5 mg	Xyzal (scored)	UCB

Comparative Pricing

This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 04/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.

Xyzal 5MG Tablets (SANOFI-AVENTIS U.S.): 90/$298.78 or 270/$855.82

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions November 01, 2008. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

References

1. UCB Inc. Xyzal (levocetirizine dihydrochloride) tablets prescribing information. 2007 May. From website.

2. Devalia JL, De Vos C, Hanotte F et al. A randomized, double-blind, crossover comparison among cetirizine, levocetirizine, and ucb 28557 on histamine-induced cutaneous responses in healthy adult volunteers. Allergy. 2001; 56:50-57. [PubMed 11167352]

3. Tillement JP, Testa B, Brée F. Compared pharmacological characteristics in humans of racemic cetirizine and levocetirizine, two histamine H₁-receptor antagonists. Biochem Pharmacol. 2003; 66:1123-6. [PubMed 14505791]

4. Wang DY, Hanotte F, De Vos C et al. Effect of cetirizine, levocetirizine, and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers. Allergy. 2001; 56:339-43. [PubMed 11284803]

5. Ciprandi G, Cirillo I, Vizzaccaro A, Tosca MA. Levocetirizine improves nasal obstruction and modulates cytokine pattern in patients with seasonal allergic rhinitis: a pilot study. Clin Exp Allergy. 2004; 34(6): 958-964. [PubMed 15196286]

6. de Blic J, Wahn U, Billard E et al. Levocetirizine in children: evidenced efficacy and safety in a 6-week randomized seasonal allergic rhinitis trial. Pediatr Allergy Immunol. 2005; 16:267-75. [PubMed 15853959]

7. Day JH, Briscoe MP, Rafeiro E et al. Comparative clinical efficacy, onset and duration of action of levocetirizine and desloratadine for symptoms of seasonal allergic rhinitis in subjects evaluated in the Environmental Exposure Unit (EEU). Int J Clin Pract. 2004; 58:109-18. [PubMed 15055856]

8. Horak F, Zieglmayer PU, Zieglmayer R et al. Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration. Br J Clin Pharmacol. 2005; 60:24-31. [PubMed 15963090]

9. Ciebiada M, Gorska-Ciebiada M, DuBuske LM et al. Montelukast with desloratadine or levocetirizine for the treatment of persistent allergic rhinitis. Ann Allergy Asthma Immunol. 2006; 97:664-71. [PubMed 17165277]

10. Pasquali M, Baiardini I, Rogkakou A et al. Levocetirizine in persistent allergic rhinitis and asthma: effects on symptoms, quality of life and inflammatory parameters. Clin Exp Allergy. 2006; 36:1161-7. [PubMed 16961716]

11. Potter PC for the Paediatric Levocetirizine Study Group. Efficacy and safety of levocetirizine on symptoms and health-related quality of life of children with perennial allergic rhinitis: a double-blind, placebo-controlled randomized clinical trial. Ann Allergy Asthma Immunol. 2005; 95:175-80. [PubMed 16136768]

12. Potter PC for the Study Group. Levocetirizine is effective for symptom relief including nasal congestion in adolescent and adult (PAR) sensitized to house dust mites. Allergy. 2003; 58:893-9. [PubMed 12911418]

13. Kapp A, Pichler WJ. Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study. Int J Dermatol. 2006; 45:469-74. [PubMed 16650180]

14. Nettis E, Colanardi MC, Barra L et al. Levocetirizine in the treatment of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. Br J Dermatol. 2006; 154:533-8. [PubMed 16445787]

15. Leynadier F, Mees K, Arendt C et al. Efficacy and safety of levocetirizine in seasonal allergic rhinitis. Acta Otorhinolaryngol Belg. 2001; 55:305-12. [PubMed 11859651]

16. Pfizer Labs. Zyrtec (cetirizine hydrochloride) tablets and syrup prescribing information. New York, NY; 2004 Jul.

17. Pfizer Laboratories. Zyrtec (cetirizine hydrochloride) tablets product monograph. New York, NY: Undated.

18. Benedetti MS, Plisnier M, Kaise J et al. Absorption, distribution, metabolism and excretion of [¹⁴C] levocetirizine, the R enantiomer of cetirizine, in healthy volunteers. Eur J Clin Pharmacol. 2001; 57:571-82. [PubMed 11758635]

19. Grant JA, Riethuisen JM, Moulaert B et al. A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects. Ann Allergy Asthma Immunol. 2002; 88:190-7. [PubMed 11868924]

20. Simons FER. H₁-Receptor antagonists: comparative tolerability and safety. Drug Saf. 1994; 10:350-80. [IDIS 359177] [PubMed 7913608]

21. Reviewers’ comments (for cetirizine).

22. Pfizer Inc. Manufacturer’s comments (for cetirizine).

23. Borge PA. Problems in allergic rhinitis. Arzneimittelforschung. 1982; 32:1199-201. [PubMed 6891258]

24. Anon. Treatment of seasonal and perennial rhinitis. BMJ. 1981; 283:808-10. [PubMed 6117350]

25. Food and Drug Administration. Over-the-counter drugs: establishment of a monograph for OTC cold, cough, allergy, bronchodilator and antiasthmatic products. [21 CFR 341] Fed Regist. 1976; 41:38312-424.

26. Douglas WW. Histamine and 5-hydroxytryptamine (serotonin) and their antagonists. In: Gilman AG, Goodman LS, Rall TW et al, eds. Goodman and Gilman’s the pharmacologic basis of therapeutics. 7th ed. New York: Macmillan Publishing Company; 1985:605-38.

27. Cirillo VJ, Tempero KF. The pharmacology and therapeutic use of H1 and H2 antihistamines. In: Miller RR, Greenblatt DJ, eds. Drug therapy reviews. Vol 2. New York: Elsevier/North Holland Inc; 1979:24-47.

28. AMA Division of Drugs. AMA drug evaluations. 5th ed. Chicago: American Medical Association; 1983:1465-79.

29. Church JA. Allergic rhinitis: diagnosis and management. Clin Pediatr (Philadelphia). 1980; 19:655-9.

30. Food and Drug Administration. Cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; tentative final monograph for OTC antihistamine drug products. [21 FR Part 341] Fed Regist. 1985; 50:2200-18.

31. Holgate S. Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever. Thorax. 1985; 40:399.

32. Bachert C, Bousquet J, Canonica W et al for the XPERT Study Group. Levocetirizine improves quality of life and reduces costs in long-term management of persistent allergic rhinitis. J Allergy Clin Immunol. 2004; 114:838-44. [PubMed 15480324]

33. UCB, Inc., Smyrna, GA: Personal communication.

34. Anon. Drugs for allergic disorders. Treat Guidel Med Lett. 2007; 5:71-80.

35. Bree F, Thiault L, Gautiers G et al. Blood distribution of levocetirizine, a new non-sedating histamine H₁-receptor antagonist, in humans. Fundam Clin Pharmacol. 2002; 16:471-8. [PubMed 12685505]

More Xyzal resources

• Xyzal Side Effects (in more detail)
• Xyzal Dosage
• Xyzal Use in Pregnancy & Breastfeeding
• Drug Images
• Xyzal Drug Interactions
• Xyzal Support Group
• 59 Reviews for Xyzal - Add your own review/rating

• Xyzal Prescribing Information (FDA)


• Xyzal Consumer Overview


• Xyzal Advanced Consumer (Micromedex) - Includes Dosage Information


• Xyzal MedFacts Consumer Leaflet (Wolters Kluwer)


• Levocetirizine Prescribing Information (FDA)

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Stadmed Mesulid

Stadmed Mesulid may be available in the countries listed below.

Ingredient matches for Stadmed Mesulid

Nimesulide

Nimesulide is reported as an ingredient of Stadmed Mesulid in the following countries:

• India

International Drug Name Search

Sodium Aurotiosulfate

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

M01CB02

CAS registry number (Chemical Abstracts Service)

0010210-36-3

Chemical Formula

Au-Na3-O6-S4·2H2O

Molecular Weight

526

Therapeutic Categories

Anti-inflammatory agent

Disease-modifying antirheumatic drug, DMARD

Chemical Name

Thiosulfuric acid (H₂S₂O₃), gold(¹+) sodium salt (2:1:3), dihydrate

Foreign Names

• Natrii aurotiosulfas (Latin)
• Natrium aurothiosulfat (German)
• Aurotiosulfate de sodium (French)
• Aurotiosulfato sodico (Spanish)

Generic Names

• Aurotiosulfato di sodio (OS: DCIT)
• Aurothiosulfate de sodium (IS)
• Sodium Aurothiosulfate (IS)

Brand Names

• Crytioro
  Drag Pharma, Chile



• Fosfocrisolo
  Zambon, Italy

International Drug Name Search

Glossary

DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Etilefrina Larjan

Etilefrina Larjan may be available in the countries listed below.

Ingredient matches for Etilefrina Larjan

Etilefrine

Etilefrine hydrochloride (a derivative of Etilefrine) is reported as an ingredient of Etilefrina Larjan in the following countries:

• Argentina

International Drug Name Search

Synphasic

Synphasic may be available in the countries listed below.

Ingredient matches for Synphasic

Ethinylestradiol

Ethinylestradiol is reported as an ingredient of Synphasic in the following countries:

• Australia


• Canada

Norethisterone

Norethisterone is reported as an ingredient of Synphasic in the following countries:

• Australia


• Canada

International Drug Name Search

Simvastatine Mylan

Simvastatine Mylan may be available in the countries listed below.

Ingredient matches for Simvastatine Mylan

Simvastatin

Simvastatin is reported as an ingredient of Simvastatine Mylan in the following countries:

• Belgium

International Drug Name Search

Salbutam

Salbutam may be available in the countries listed below.

Ingredient matches for Salbutam

Salbutamol

Salbutamol is reported as an ingredient of Salbutam in the following countries:

• Peru

International Drug Name Search

Histex Pd 12

Pronunciation: kar-bi-NOX-a-meen
Generic Name: Carbinoxamine Maleate/Tannate
Brand Name: Histex Pd 12

Histex Pd 12 is used for:

Treating allergy symptoms such as runny nose, watery/itchy eyes, rash, or hives. It may also be used for other conditions as determined by your doctor.

Histex Pd 12 is an antihistamine. It works by blocking the action of histamine, which reduces the symptoms of an allergic reaction.

Do NOT use Histex Pd 12 if:

• you are allergic to any ingredient in Histex Pd 12


• you are taking sodium oxybate (GHB) or a monoamine oxidase (MAO) inhibitor (eg, phenelzine)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Histex Pd 12:

Some medical conditions may interact with Histex Pd 12. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have asthma, glaucoma, difficulty urinating, a stomach or bladder blockage, prostate problems, increased pressure in the eye, an underactive thyroid, heart disease, or high blood pressure

Some MEDICINES MAY INTERACT with Histex Pd 12. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturates (eg, phenobarbital), MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects of Histex Pd 12 may be increased


• Sodium oxybate (GHB) because side effects, such as an increase in sleep duration and drowsiness leading to unconsciousness or coma, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Histex Pd 12 may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Histex Pd 12:

Use Histex Pd 12 as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Histex Pd 12 may be taken with or without food.


• Shake well before using.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Histex Pd 12 and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Histex Pd 12.

Important safety information:

• Histex Pd 12 may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Histex Pd 12. Using Histex Pd 12 alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Use Histex Pd 12 with caution in the ELDERLY because they may be more sensitive to its effects.


• Use Histex Pd 12 with extreme caution in CHILDREN younger than 9 months of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is unknown if Histex Pd 12 can cause harm to the fetus. If you become pregnant while taking Histex Pd 12, discuss with your doctor the benefits and risks of using Histex Pd 12 during pregnancy. It is unknown if Histex Pd 12 is excreted in breast milk. Do not breast-feed while taking Histex Pd 12.

Possible side effects of Histex Pd 12:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; blurred vision; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; headache; heartburn; nausea; nervousness; thickening of mucus in the nose or throat; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Histex Pd2 side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include double vision; excitement; frequent urination; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness. In children, symptoms may include abnormal eye movement; abnormal tongue movement; agitation; bizarre behavior; confusion; difficulty urinating; excitation; flushed face; irritability; loss of consciousness; loss of coordination; restlessness; seizures; slurred speech; tiredness; trembling; twitching.

Proper storage of Histex Pd 12:

Store Histex Pd 12 between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Histex Pd 12 out of the reach of children and away from pets.

General information:

• If you have any questions about Histex Pd 12, please talk with your doctor, pharmacist, or other health care provider.


• Histex Pd 12 is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Histex Pd 12. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Histex Pd 12 resources

• Histex Pd 12 Side Effects (in more detail)
• Histex Pd 12 Use in Pregnancy & Breastfeeding
• Drug Images
• Histex Pd 12 Drug Interactions
• Histex Pd 12 Support Group
• 2 Reviews for Histex Pd2 - Add your own review/rating

• Histex Pd 12 Concise Consumer Information (Cerner Multum)


• Carbinoxamine Prescribing Information (FDA)


• Arbinoxa Concise Consumer Information (Cerner Multum)


• Arbinoxa Prescribing Information (FDA)


• Carbinoxamine Maleate Monograph (AHFS DI)


• Palgic Prescribing Information (FDA)

Compare Histex Pd 12 with other medications

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